e-book International Review of Cell and Molecular Biology: 276

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Emphasis on neuroendocrinology of steroid hormone involvement in reproductive behaviors. Analysis of weekly colloquia in the biological sciences. Signal transduction between cells of multicellular eukaryotic organisms examined in the context of specialized functions that include: nutrition, hormones and neurotransmitters, vision, muscle contraction, adhesion, and the immune system.

The evolution of cancer based on mutations in these signaling systems. Communication between neurons. Physiology of synaptic transmission; varying forms of neuronal plasticity; acquisition, encoding, and retrieval of memory. Modern molecular genetics techniques applied to complex brain processes. Animal models of learning, behavioral plasticity, and neuropsychiatric diseases. Development, presentation and implementation of research proposals, and discussions of research.

International Review of Cell and Molecular Biology Volume 319

Required for senior biology, molecular biology, biochemistry, and behavioral neuroscience majors pursuing departmental honors. Departmental permission required. Laboratory research under tutorial with a faculty member. Must have junior standing. Literature review and design of project in selected area, execution of the project, final report and presentation.

ISO/TC 276

Intended for senior majors in BIOS only. Students learn expectations and fundamental skills related to success in the biological sciences. The course is designed to help students make the most out of their graduate education.

Students learn the principles underlying fundable, publishable research, and how these general principles can be applied to their specific research area. They learn to write and review manuscripts and grant proposals by serving on a mock editorial board and scientific review panel.

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They gain experience in giving oral presentations. Readings are from texts on scientific writing and research styles, and from original journal articles and grant proposals written by the faculty. Required of all Integrative Biology graduate students. Theoretical and empirical issues in biopsychology.

Must have graduate standing. Research, conferences, and reports on selected topics not covered in the general graduate offerings. An advanced seminar in current developments including departmental research. Required for candidates for graduate degrees in molecular biology. Laboratory investigations in one of the department's research areas.


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Responsible practice in research. Training in general laboratory methods; human subjects concerns; radiation safety; chemical hazards; aseptic technique; physical, mechanical, biological, and fire hazards; animal welfare. Occupational and workplace considerations. Recombinant DNA guidelines; patent and proprietary rights; controversies over applications of science. Appropriate aspects required of investigators in all departmental research projects.


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Readings in the current literature, demonstrations and laboratory exercises exploring the applications of comparative methods to the analysis of evolutionary patterns at a range of morphological levels molecular and macroscopic. Students will also learn experimental approaches to testing relationships between form and function in vertebrates.

Emphasis will be on the musculoskeletal and nervous systems. Readings and discussions on selected topics not covered in the general graduate offerings. Cell structure and biochemistry, as related to specialized cell functions.

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Sensory systems that detect metabolic energy availability and affect the behavior of humans and other animals: food intake and body weight regulation, sexual and parental behavior, aggression, learning, and body temperature regulation. Genetic and hormonal events mediating the development and expression of sexual dimorphisms in physiology and behavior. Current theoretical models; emphasis on biochemical, neuroanatomical and molecular biological considerations.

Physiology of synaptic transmission; varying forms of neuronal plasticity; acquisition, encoding and retrieval of memory. Molecular aspects of cell structure, cell motility, intracellular transport; and biomembrane dynamics. This course is designed to provide an overview of core principles of neuroscience through exploration of sensory systems. The course will provide an intensive review of fundamental neural signaling followed by a broad introduction to the major sensory pathways.

Focus will be on major organizing principles of neural systems, and information processing. Student discussions and presentations will incorporate current literature and concepts. Evolution at the level of individual genes, proteins, and genomes. Lectures and discussion of papers from the recent primary literature. Examples of molecular evolution in nature, laboratory model systems, and human pathogens.

Lectures and readings from the primary literature on current research in amphibian and reptilian biology. Two lectures, one discussion session and one laboratory or field trip. Current research problems in cell biology.

Biological Sciences (BIOS) < Lehigh University

Current research in molecular genetics. Current research problems in developmental biology. Discussion-based seminar course covering readings from classical and current literature, including both theoretical and empirical contributions.


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Topics will be included species concepts, reproductive isloation, mechanisms and modes of speciation, and current approaches to studying speciation. Biochemical basis of human diseases involving abnormal metabolism of proteins, nucleic acids, carbohydrates, and lipids. Emphasis on the correlation of the clinical presentation of disease processes seen as physiological dysfunctions with clinical laboratory methods. Lectures, student presentations, and clinical case discussions. Critical evaluation of the theoretical foundation in sociobiology.

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Emphasis placed on kinship, altruism, mate choice, parental investment, parent-offspring conflict, etc. Lectures and seminars. Theoretical, philosophical and methodological foundations of the classification of eukaryotic organisms and the manner in which systematic theory and method relate to evolutionary theory. Fundamental mechanisms underlying neural development. Early events leading to the induction of the neuroectoderm and the reorganization of the vertebrate central nervous system during adulthood and aging. Major developmental events such as phenotype commitment, cell migration, differentiation and growth cone guidance.

Emphasis on the interplay between concepts emerging from organismal and molecular levels of analyses. Graduate level study of the neuroanatomy and neurochemistry of systems that underlie behavior in vertebrates. Emphasis will be on the traditional and novel methodologies used to reveal neuroanatomical pathways as well as the function of these pathways. A seminar course that covers current primary literature on the hormone-nervous system interactions that underlie physiology and behavior.

The course covers the neuroendocrinology of reproduction, sex behavior, parental behavior, social behavior, agonistic and territorial behavior, learning and memory, homeostasis caloric, nutritional, water and salt balance, temperature regulation , circadian rhythms and seasonality in a variety of vertebrates. Comparative analysis of several eukaryotes as model systems in cell biology, developmental biology, genetics, and molecular biology.

An examination of the principles underlying nucleic acid structure including stereochemistry, electrostatics, hydration, torsional constraints, sequence specific effects, and interaction with nuclear proteins. Special emphasis will be placed on DNA structure. Must have completed one year of biochemistry and one year of physical chemistry or consent of department required.

An examination of the principles underlying protein structure including stereochemistry, preferred tertiary structures, protein homology, excluded volume effects, time dependent structural fluctuations, and prediction of protein structure from sequence information. Signal transduction between and within cells of multicellular organisms examined in the context of specialized functions that include: nutrition, hormones and neurotransmitters, vision, muscle contraction, adhesion and the immune system.

Lecture, discussion, and student presentations. The study of lipids and lipid membranes similar to those found in mammalian cells including methods of synthesis, surface activity, bilayer and micellar structures, lipid mixing, fluidity, permeability and membrane stability. Special emphasis will be given to the current evidence for and against the lipid raft hypothesis.

Study of proteins, carbohydrates, lipids, nucleic acids and other biological substances.